In recent years recombinant preparations for specific prevention of infectious laryngotracheitis (ILT) (vector vaccine) have been put into veterinary practice in the USA and many other countries. However, there are published reports that put in doubt the efficacy of the preparations. In this regard, examination of avian immune response to the ILT vector vaccine was considered as relevant.
Staff members of the Laboratory for Poultry Disease Prevention of the Rosselkhoznadzor subordinate FGBI “Federal Centre for Animal Health” set up an experiment. One-day-old pullets, on-farm vaccinated with the recombinant ILT vector vaccine ; not-vaccinated SPF-cockerels and chickens were used in the experiment. At the age of 28-days old all birds were vaccinated with ILT embryo vaccine. Concentration of specific serum antibodies was detected using commercial diagnostic kit before and after the booster vaccination with ILT embryo vaccine (based on the attenuated virus).
No significant difference was determined between the average titers in the groups both before the booster vaccination and in the process of humoral immune response development after the booster vaccination.
Consequently, the preliminary immunization with the vector preparation did not prevent the establishment and development of boostered vaccine virus in poultry.
FGBI “ARRIAH” Press Office